户外运动联合中药雾化干预高度近视合并视疲劳的临床疗效观察*

作者：张舒燕1,2，计 宏1，沙咏怡1，袁 媛3，解 云1

单位：1.上海市闵行区中西医结合医院，上海 200241； 2.上海中医药大学附属龙华医院，上海 200032； 3.南京华厦眼科医院，江苏 南京 210000

引用：引用：张舒燕，计宏，沙咏怡，袁媛，解云.户外运动联合中药雾化干预高度近视合并视疲劳的临床疗效观察[J].中医药导报,2026,32(1):113-118.

DOI：10.13862/j.cn43-1446/r.2026.01.019

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摘要：

目的：观察户外运动联合中药雾化对近距离工作致高校学生高度近视合并视疲劳患者的改善作用。方法：收集华东师范大学在校学生有效问卷1 768份，并对其用眼行为进行统计分析；采用单因素、多因素Logistic回归分析Conlon视觉不适量表中视疲劳的影响因素。此外，选择该校120例高度近视伴有视疲劳的患者，随机分为对照组和治疗组（各60例）。对照组1周户外运动3次，治疗组在此基础上增加每周2次清热滋阴方中药雾化治疗，持续治干预3个月。于干预前后测量视疲劳评分、裸眼视力、眼轴长度、调节功能（调节幅度、调节灵敏度和正负相对调节积分）。结果：在校学生每天使用电子产品>6 h的占30.75%，而每天运动时间少于2 h的占80.37%（1 421/1 768），近视年限（OR=1.974）、眼表慢性异常（OR=7.665）、调节功能（OR=1.239）、每天近距离学习时间（OR=3.334）是视疲劳的主要危险因素（P<0.05）。对照组患者干预3个月后视疲劳评分、裸眼视力、眼轴长度、调节幅度积分、调节灵活度积分和正、负相对调节积分与干预前比较，差异无统计学意义（P>0.05）。治疗组患者干预3个月后视疲劳评分较干预前降低（P<0.01），裸眼视力、调节幅度积分、调节灵活度积分、正相对调节积分、负相对调节积分均较干预前升高（P＜0.01）。此外，视疲劳评分低于对照组（P＜0.01），裸眼视力、调节幅度积分、调节灵活度积分、正相对调节积分、负相对调节积分均高于对照组（P＜0.01）。两组患者干预3个月后眼轴长度比较，差异无统计学意义（P>0.05）。结论：户外活动结合中药雾化对高校学生高度近视合并视疲劳有显著的改善效果，具备较好的临床应用前景和推广价值。

关键词：高度近视；视疲劳；清热滋阴方；中药雾化；户外运动

Abstract：

Objective: To observe the improvement effect of outdoor exercise combined with TCM nebulization on high myopia and visual fatigue caused by prolonged close-distance work in college students. Methods: A total of 1,768 valid questionnaires were collected from students at East China Normal University, and their eye-use behaviors were statistically analyzed. Single-factor and multi-factor logistic regression analyses were used to identify influencing factors for visual fatigue using the Conlon Visual Discomfort Scale. Additionally, 120 high myopia patients with visual fatigue from the university were selected and randomly divided into a control group and a treatment group, with 60 cases in each group. The control group performed outdoor exercise three times a week. The treatment group received additional herbal nebulization therapy using Heat-Clearing and Yin-Nourishing Formula (清热滋阴方) twice a week for 3 months. Visual fatigue scores, uncorrected visual acuity (UCVA), axial length, and accommodation function parameters (accommodative amplitude, accommodative sensitivity, and positive/negative relative accommodation scores) were measured before and after treatment. Results: Among the students, 30.75% used electronic devices for >6 hours daily, while 80.37% (1,421/1,768) exercised for less than 2 hours daily. Duration of myopia (OR=1.974), chronic ocular surface abnormalities (OR=7.665), accommodation function (OR=1.239), and daily close-range study time (OR=3.334) were the main risk factors for visual fatigue (P<0.05). In the control group, there were no significant differences in visual fatigue scores, UCVA, axial length, accommodative amplitude score, accommodative flexibility score, and positive/negative relative accommodation scores after 3 months of treatment compared to before treatment (P>0.05). In the treatment group, visual fatigue scores decreased significantly after 3 months (P<0.01), while UCVA, accommodative amplitude score, accommodative flexibility score, positive relative accommodation score, and negative relative accommodation score all increased (P<0.01). Furthermore, visual fatigue scores in the treatment group were lower than those in the control group (P<0.01), while UCVA and the aforementioned accommodation parameters were higher (P<0.01). There was no significant difference in axial length between the two groups after 3 months (P>0.05). Conclusion: The combination of outdoor activities and TCM nebulization demonstrates notable efficacy in alleviating high myopia and visual fatigue in college students, showing promising clinical application prospects and promotion value.

Key words：high myopia; visual fatigue; Heat-Clearing and Yin-Nourishing Formula; traditional Chinese medicine nebulization; outdoor exercise

发布时间：2026-01-30

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