芪夏益气通脉方联合维拉帕米治疗中老年稳定性心绞痛的疗效观察*

作者：胡学敬1，闫茹玉1，王 龙1，兰泽毅1，柳彩霞1，刘 敏1，常 帅2

单位：1.衡水市中医医院，河北 衡水 053000； 2.阜城县人民医院，河北 衡水 053000

引用：引用：胡学敬，闫茹玉，王龙，兰泽毅，柳彩霞，刘敏，常帅.芪夏益气通脉方联合维拉帕米治疗中老年稳定性心绞痛的疗效观察[J].中医药导报,2026,32(1):103-106.

DOI：10.13862/j.cn43-1446/r.2026.01.017

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摘要：目的：观察芪夏益气通脉方联合维拉帕米治疗中老年稳定性心绞痛（SAP）的疗效。方法：将2024年1—6月衡水市中医医院收治的86例中老年SAP患者随机分为对照组、观察组，每组43例。对照组患者采用维拉帕米治疗，观察组患者采用芪夏益气通脉方联合维拉帕米治疗。比较两组患者的临床疗效，以及治疗前后的中医证候积分、心电图运动平板试验结果和炎症因子水平。结果：对照组剔除1例，观察组剔除和脱落3例，最终纳入对照组42例、观察组40例。两组患者治疗后中医证候积分均降低，且观察组积分低于对照组（P＜0.05）；观察组临床总有效率为97.50%（39/40），明显高于对照组的73.81%（31/42）（P＜0.05）；两组患者治疗后运动时间均增加，且观察组运动时间长于对照组（P＜0.05）；两组患者治疗后白细胞介素-6（IL-6）、超敏C反应蛋白（hs-CRP）均降低，且观察组2个指标水平均低于对照组（P＜0.05）。结论：芪夏益气通脉方联合维拉帕米能够有效减轻中老年SAP患者的临床症状，增加其运动时间，降低其炎症因子水平，提高临床疗效。

关键词：稳定性心绞痛；中老年；芪夏益气通脉方；维拉帕米；临床研究

Abstract：

Objective: To observe the efficacy of Qixia Yiqi Tongmai Formula (芪夏益气通脉方) combined with verapamil in treating stable angina pectoris (SAP) in middle-aged and elderly patients. Methods: Eighty-six middle-aged and elderly SAP patients admitted to Hengshui Hospital of Traditional Chinese Medicine from January to June 2024 were randomly divided into a control group and an observation group, with 43 cases in each group. The control group received verapamil treatment, while the observation group received Qixia Yiqi Tongmai Formula combined with verapamil. Clinical efficacy, traditional Chinese medicine (TCM) syndrome scores, treadmill exercise electrocardiogram results, and inflammatory factor levels before and after treatment were compared between the two groups. Results: One case was excluded from the control group, and three cases were excluded or discontinued from the observation group. Thus, 42 cases in the control group and 40 cases in the observation group were finally included for analysis. After treatment, TCM syndrome scores decreased in both groups, with the observation group showing lower scores than the control group (P<0.05). The total clinical effective rate was 97.50% (39/40) in the observation group, significantly higher than 73.81% (31/42) in the control group (P<0.05). Exercise time increased in both groups after treatment, with the observation group having longer exercise time than the control group (P<0.05). Levels of interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) decreased in both groups after treatment, with the observation group showing lower levels of both indicators than the control group (P<0.05). Conclusion: Qixia Yiqi Tongmai Formula combined with verapamil can effectively alleviate symptoms, increase exercise duration, reduce inflammatory factor levels, and improve clinical efficacy in middle-aged and elderly patients with SAP.

Key words：stable angina pectoris; middle-aged and elderly; Qixia Yiqi Tongmai Formula; verapamil; clinical study

发布时间：2026-01-30

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