梁王茶化学成分、药理作用研究进展及质量标志物（Q－Marker）预测分析*

作者：陈思念1，孙华聪1，戴相仙1，徐志霖1，谭文红1，2

单位：1.云南中医药大学民族医药学院，云南 昆明 650500； 2.云南省傣医药与彝医药重点实验室，云南 昆明 650000

引用：引用：陈思念，孙华聪，戴相仙，徐志霖，谭文红.梁王茶化学成分、药理作用研究进展及质量标志物(Q－Marker)预测分析[J].中医药导报,2025,31(9):83-90,96.

DOI：10.13862/j.cn43-1446/r.2025.09.014

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摘要：

总结梁王茶的化学成分、药理作用及其应用研究进展，并在此基础上结合质量标志物的概念，从化学成分可测性、化学成分与药理作用相关性、传统药性、药效相关性四方面，预测分析梁王茶的质量标志物。梁王茶含有三萜皂苷类、酚酸类、木脂素类化学成分，以及少量黄酮类、挥发油类等其他化学成分，具有镇痛、抗炎、抗氧化、抑制前列腺增生、保肝、抗菌、抗病毒及抗疟等功效。三萜皂苷类为主要药效物质。建议将梁王茶苷Ⅱ、异叶梁王茶苷Ⅳ、丁香脂素、槲皮素、山柰酚、儿茶素、水杨酸和肉桂酸作为梁王茶质量标志物的选择参考。

关键词：梁王茶；化学成分；药理作用；质量标志物

Abstract：This review summarizes the research progress on the chemical constituents, pharmacological effects, and applications of Metapanax delavayi. Based on the concept of quality markers (Q-markers), a predictive analysis of its Q-markers was conducted by integrating four aspects: measurability of chemical constituents, correlation between chemical constituents and pharmacological effects, traditional medicinal properties, and efficacy correlation. Metapanax delavayi contains triterpenoid saponins, phenolic acids, and lignans, along with smaller quantities of other components such as flavonoids and volatile oils. It exhibits various pharmacological activities including analgesia, anti-inflammation, antioxidation, inhibition of prostate hyperplasia, hepatoprotection, antibacterial, antiviral, and antimalarial effects. Triterpenoid saponins are identified as the primary active constituents. It is suggested that liangwanoside Ⅱ, yiyeliangwanoside Ⅳ, syringaresinol, quercetin, kaempferol, catechin, salicylic acid, and cinnamic acid could serve as potential Q-markers for Metapanax delavayi.

Key words：Liangwangcha (Metapanax delavayi); chemical constituents; pharmacological effects; quality markers (Q-markers)

发布时间：2026-01-08

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