和调督任法治疗眼肌型重症肌无力的疗效观察*

作者：吕少将1，陈英华2，白晶银3

单位：1.黑龙江中医药大学，黑龙江 哈尔滨 150040； 2.黑龙江中医药大学附属第一医院，黑龙江 哈尔滨 150040； 3.黑龙江省中医医院，黑龙江 哈尔滨 150040

引用：引用：吕少将，陈英华，白晶银.和调督任法治疗眼肌型重症肌无力的疗效观察[J].中医药导报,2025,31(6):111-114,134.

DOI：10.13862/j.cn43-1446/r.2025.06.019

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摘要：

目的：观察和调督任法治疗眼肌型重症肌无力（OMG）患者的临床疗效。方法：将60例OMG患者按照随机数字表法分为观察组（30例）和对照组（30例）。对照组患者予溴吡斯的明片口服治疗；观察组患者在对照组治疗基础上予和调督任法针刺治疗，两组均治疗12周。治疗结束后观察两组患者治疗前后重症肌无力眼部量表O-QMG、重症肌无力患者生存质量MG-QOL-15评分及药物使用剂量与种类。结果：治疗过程中，观察组脱落4例，对照组脱落3例。治疗后，观察组总有效率96.2%，对照组92.6%，两组患者总有效率比较，差异无统计学意义（P＞0.05）；治疗后，两组患者O-QMG评分、MG-QOL-15评分均低于治疗前（P＜0.05），且观察组患者O-QMG评分、MG-QOL-15评分低于对照组，差异有统计学意义（P＜0.05）；治疗后，观察组患者溴吡斯的明使用剂量较治疗前明显减少，且观察组用药量少于对照组，差异有统计学意义（P＜0.05）；治疗后，两组患者各中医证型O-QMG评分均减少，差异有统计学意义（P＜0.05）；治疗后，两组患者O-QMG评分均降低，且观察组中肝郁脾虚证患者下降水平明显高于对照组，差异有统计学意义（P＜0.05），其余证型差异无统计学意义（P＞0.05）。结论：和调督任法针刺治疗可改善OMG患者症状，减少患者药物使用剂量，有助于患者日常生活活动能力提升，疗效确切。

关键词：眼肌型重症肌无力；和调督任；针刺；疗效观察

Abstract：

Objective: To evaluate the clinical efficacy of "Harmonizing Governor and Conception Vessels" acupuncture (HGCV) in treating ocular myasthenia gravis (OMG). Methods: Sixty OMG patients were randomly divided into observation group (n=30) and control group (n=30). The control group received pyridostigmine bromide tablets, while the observation group received additional HGCV acupuncture for 12 weeks. Outcomes included Ocular-QMG scale (O-QMG), Myasthenia Gravis Quality of Life-15 (MG-QOL-15) scores, and medication dosage. Results: During the treatment period, 4 cases in the observation group and 3 cases in the control group were lost to follow-up. After treatment, the total effective rates were 96.2% in the observation group and 92.6% in the control group, with no statistically significant difference between groups (P>0.05). Both groups showed significant reductions in O-QMG and MG-QOL-15 scores compared to baseline (P<0.05), with the observation group demonstrating significantly lower scores than the control group (P<0.05). The pyridostigmine bromide dosage was significantly reduced in the observation group compared to both pretreatment levels and the control group (P<0.05). All TCM syndrome types exhibited significant reductions in O-QMG scores (P<0.05). While both groups showed decreased O-QMG scores, patients with liver depression-spleen deficiency syndrome in the observation group achieved significantly greater reduction than the control group (P<0.05), with no significant differences observed in other syndrome types (P>0.05). Conclusion: HGCV acupuncture alleviates OMG symptoms, reduces medication dependence, and improves daily functioning.

Key words：ocular myasthenia gravis; Harmonizing Governor and Conception Vessels; acupuncture; therapeutic evaluation

发布时间：2026-01-04

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