基于文献计量学的中药苦杏仁研究趋势与热点可视化分析*
作者：张剑航1，廉 坤1，宋志广1，毛恺妮1，冯雨静1，龙昱艳1，李 花1,2，刘旺华1,2,3
单位：1.湖南中医药大学中医诊断学湖南省重点实验室，湖南 长沙 410208； 2.湖南中医药大学药食同源功能性食品工程技术研究中心，湖南 长沙 410208； 3.湖南中医药大学中医心肺病证辨证与药膳食疗重点研究室，湖南 长沙 410208
引用：引用：张剑航，廉坤，宋志广，毛恺妮，冯雨静，龙昱艳，李花，刘旺华.基于文献计量学的中药苦杏仁研究趋势与热点可视化分析[J].中医药导报,2025,31(7):171-179,186.
DOI：10.13862/j.cn43-1446/r.20250625.001
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摘要：
目的：分析苦杏仁研究现状与前沿热点，为苦杏仁的科研应用、药理研究及专利技术发展提供参考依据。方法：以中国知网、万方数据库、维普数据库为中文文献数据来源，Web of Science核心合集为英文文献数据来源，检索1980—2024年苦杏仁相关文献，运用CiteSpace和VOSviewer软件分析研究国家、机构、作者合作、期刊共引和被引情况，并绘制关键词共现图、聚类图和突现图。结果：纳入570篇中文文献和103篇英文文献，整体发文量呈上升趋势。中文文献发文量最多的机构是陕西师范大学（26篇），英文文献发文量最多的机构是Islamic Azad University（7篇）。中文文献发文量最多的期刊为《中国中药杂志》（27篇），英文文献中发文量较多的期刊为Food Science and Biotechnology（4篇）和Foods（4篇）。中文文献发文量最多的作者是张清安（14篇），英文文献发文量最多的作者是HOSSEINI E（6篇）、KOLESAROVA A（6篇）。中文文献中苦杏仁出现频数最高（267），英文文献中bitter almond（苦杏仁）频数最高（32）。关键词聚类生成了14个中文关键词聚类和12个英文关键词聚类。中文文献突现词有20个，突现性最高的是“含量测定”；英文文献突现词有20个，突现性最高的是“antioxidant”（抗氧化剂）。结论：当前苦杏仁研究聚焦于抗癌活性、抗氧化机制及资源开发，但面临国际合作不足与成果转化滞后等挑战；未来的研究需加强跨学科协作，推动种质保护、技术创新与临床应用转化，以实现其标准化生产及多领域应用。
关键词：苦杏仁；可视化分析；文献计量学；抗氧化；癌症
Abstract：
Objective:
To analyze the current research status and frontier hotspots of bitter almond
(Prunus armeniaca L.), providing a reference basis for its scientific
application, pharmacological research, and patent technology development.
Methods: Chinese literature was retrieved from CNKI, Wanfang Database, and VIP
Database, while english literature was sourced from the Web of Science Core
Collection. Literatures related to bitter almond from 1980 to 2024 were
retrived. CiteSpace and VOSviewer software were used to analyze research
countries, institutions, author cooperation, journal co-citation and citation
status, and to draw keyword co-occurrence maps, clustering maps, and burst
maps. Results: A total of 570 Chinese articles and 103 english articles were
included, with an overall upward trend in publication volume. The institution
with the highest Chinese publication output was Shaanxi Normal University (26
articles), while Islamic Azad University led english publications (7 articles).
The China Journal of Chinese Materia Medica (27 articles) ranked first in
Chinese journal contributions, whereas Food Science and Biotechnology (4
articles) and Foods (4 articles) were prominent in english literature. The most
prolific Chinese author was ZHANG Qing'an (14 articles), and HOSSEINI E (6
articles) and KOLESAROVA A (6 articles) topped english publications. In Chinese
literature, "bitter almond" was the highest-frequency keyword (267
occurrences), while "bitter almond" (32 occurrences) dominated
english literature. Keyword clustering identified 14 Chinese and 12 english
clusters. There are 20 Chinese burst terms, among which "content
determination" shows the highest burst strength. There are 20 english
burst terms, with "antioxidant" as the strongest burst term.
Conclusion: Current research on bitter almond focuses on anticancer activity,
antioxidant mechanisms, and resource utilization, yet faces challenges such as
insufficient international collaboration and delayed translation of research
outcomes. Future efforts should prioritize interdisciplinary collaboration,
germplasm conservation, technological innovation, and clinical application to
advance standardized production and multifunctional utilization.
Key words：bitter almond; visual analysis; bibliometrics; antioxidant; cancer
发布时间：2026-01-06
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